What is Medical Ozone Therapy?
Medical ozone therapy is one of the traditional and complementary medicine (GETAT) methods based on mixing pure medical oxygen and ozone gas in specific ratios, applied under physician control and in accordance with international standards protocols.
Ozone gas is strictly never inhaled through the respiratory tract; medical ozone applications are performed through special devices using systemic (e.g., major autohemotherapy) or local (intra-articular, intramuscular, rectal, or bagging) methods.
Biological Mechanism and Effect in the Body
Ozone is not a foreign substance that remains in the body for a long time. The moment it comes into contact with biological fluids and blood, it produces short-term, controlled oxidative signals. This controlled stimulation triggers the following mechanisms in the body:
- Redox Balance and Antioxidant Capacity: It activates intracellular antioxidant defense systems (glutathione peroxidase, superoxide dismutase).
- Nrf2 Pathway Stimulation: It supports cellular resistance by activating the Nrf2 pathway, which is the main regulator of cellular protection and antioxidant response.
- Tissue Oxygenation and Circulation: It supports capillary circulation and oxygen delivery to tissues by increasing the flexibility of red blood cells (erythrocytes).
- Inflammation Balance: It exhibits balancing effects on inflammatory signaling pathways.
In Which Situations Can It Be Considered as Supportive?
According to the Ministry of Health GETAT guidelines, ozone therapy can be considered as a supportive approach at the discretion of a physician in circulation disorders, chronic fatigue, wounds with delayed healing, musculoskeletal pains, and balancing immune functions. It should never be seen as an alternative to standard medical treatments.
Who Cannot Receive It (Contraindications)?
- Favism (Glucose-6-Phosphate Dehydrogenase enzyme deficiency),
- Uncontrolled hyperthyroidism (overactive thyroid gland),
- Severe bleeding disorders and active internal bleeding conditions,
- Severe cardiovascular instability or recent myocardial infarction (heart attack),
- Pregnancy and breastfeeding period.
Our Clinical Approach
At Dr. Cemal İsmailoğlu Clinic, medical ozone therapy is safely applied with a personalized dose and session planning by the physician after evaluating the patient's detailed medical history, accompanying diseases, medications used, and laboratory parameters.
Legal Disclaimer: All information on this page has been prepared for general informational purposes only and does not constitute diagnosis or treatment. For your health problems, examination, diagnosis, and the suitability of your treatment processes, please consult your physician.
This content has been translated using artificial intelligence technology.
